Muscle Structure and Function

The subject of muscle structure and muscle function will take more than one letter, as altitude training will also come under this heading.

 For those who wish to go further into the chemistry of muscle cross-bridge cycling etc., there are pages (Lore of Running 4th Edition) of very clear explanations and diagrams, following the muscle’s response in sequence, from its first impulse from the brain.

In these letters, I shall only attempt to cover the sections in the book, which may be helpful to the coach’s understanding of the muscle’s functions and the implications for training.

H.G.L

Types of muscle fibres

In line with the most modern classification of muscle fibre types, fibres are either defined as red, Type 1, slow- twitch, (ST), or white, Type 2, fast-twitch, (FT) fibres.

The understanding is that the Type 2 fibres (FT) contract so rapidly because they have a high myosin ATPase activity, whereas Type 1 fibres (ST) have a lower myosin ATPase activity.

However, it now seems that the situation is not quite this simple; the myosin ATPase activity is not simply either fast or slow and there may be varying grades of fastness or slowness among the Type 1(ST) and Type 2 fibres (FT). Thus, the Type 1(ST) fibres of some athletes may have contraction speeds that approach those normally found in Type 2 (FT) fibres.

In addition, the Type 2 fibres can be divided into at least five subtypes: 2a, 2b, 2c, 2ab and 2ac. The Type 2a fibre is believed to be a Type 2 fibre that is adapted for endurance exercise. The Type 2b fibre conforms to the classical (very fast and powerful) Type 2 (FT). The Type 2c fibre is of uncertain origin, and maybe, an uncommitted primitive fibre, capable of developing into either a Type 2a or a Type 1 fibre.  

More recently the Type 2c fibre has been named the Type 2x fibre. In vitro studies show that Type 2x fibres produce about twice as much power (force at speed) as Type 2a fibres, which are about five times more powerful than Type 1 fibres.

Extracts (shortened - from correspondence with Prof Noakes.)

The physiological principles from which I begin are:

So the key is to get the correct balance of both.

Specificity of Training

In studies lasting up to twelve weeks, enzyme concentrations, appear to show a gradual and progressive increase. At present it seems that the rate and magnitude of these changes is a function within limits of the total amount of muscle contractile activities. The rate can be increased either by performing more contractions in a given time period  (increasing exercise intensity) or by maintaining the same frequency of contraction for a longer period (increasing exercise duration). As will be discussed, it seems that the former method of increasing exercise intensity may produce more rapid and greater results than the latter, but at a greater risk of overtraining.…………………………

The first practical point of this research is that there is a limit to the extent to which the mitochondrial enzyme can adapt and this limit is reached more quickly, with less total training time, by performing high-intensity exercise of short duration than by running at much lower intensities for very much longer.

What practical value can be derived from this knowledge? Firstly, mitochondrial adaptations to training only occur in the trained muscle and the in muscle fibres that are active during these specific exercises. This indicates that when training for a particular event or sport, an athlete must concentrate on utilizing the correct muscle groups, and, more specifically, the appropriate muscle fibres and the appropriate metabolic pathways in those fibres.

This wisdom underlies an important principle of training, known as the ‘specificity of training’